5-HT3 antagonist
Action: Blocks the effects of serotonin at 5HT3 receptor sites located in the vagal nerve terminals and the chemoreceptor trigger zone in the CNS
See more Knowing what potential side effects may occur can help patients better manage their symptoms while taking this medication
Pre-Administration Assessment: Post Administration Evaluation: Nursing Considerations: Administer slowly over 2-5 minutes – fatal QT prolongation and VTach
Davis PT Collection
Ondansetron (brand name Zofran) is a very common medication you’ll see in the clinical setting, on your care plans, and
Zofran
This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects
Alternatives
• administer slowly over 2-5 minutes – fatal QT prolongation and VTach, respiratory arrest
Find information on Ondansetron (Zuplenz) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action
Use of ondansetron in nursing mothers beyond the immediate postpartum setting has not been studied well, but the drug is labeled for use in infants as young as 1 month of age
tired feeling
blocks effects of serotonin on vagal nerve and CNS
Nursing Considerations • administer slowly over 2-5 minutes – fatal QT prolongation and VTach, respiratory arrest • may cause headache, constipation Ondansetron (Zofran) Nursing Considerations
Figure 7
antiemetic
Using these medicines together may increase risk for more serious problems
Ondansetron works by blocking one of the body's natural substances that causes vomiting
The dosage is based on your medical condition and response Pantoprazole Nursing Interventions
Ondansetron is one of the medications most commonly used for the empiric treatment of nausea and vomiting
Trade & Generic Names Ondansetron (Zofran) Pharmacokinetics (absorption, [onset, peak, duration], distribution, metabolism, excretion) Oral ondansetron is well absorbed from the GI tract and undergoes some first-pass metabolism
Figure 7
Diarrhea, which may cause fluid and electrolyte imbalance, is a potential adverse effect of the drug
Ondansetron is not approved for use by anyone younger than 4 years old
Ondansetron Injection is indicated for the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including high-dose cisplatin
The American College of Obstetricians and Gynecologists recommends early treatment of nausea and vomiting of pregnancy to stop progression to hyperemesis gravidarum
zofran